The Core Curriculum for the Advanced Practice Hospice and Palliative Registered Nurse reflects the current knowledge in advanced hospice and palliative nursing and in professional practice. This revision reflects the expertise of APRNs from throughout the field who serve in a variety of settings and the expertise of interdisciplinary team members. The goal of the curriculum is to provide a foundation of knowledge from which APRNs can practice palliative care. In the last decade, the evidence base for palliative care has expanded. The chapters in this curriculum reflect this. To meet the rapidly changing needs of the APRN, the Core Curriculum has been reorganized. The first section, Issues in Palliative Nursing, presents an overview of the role and practice concerns. The second section, Dimensions of Care, reviews common symptoms, and psycho-social-spiritual aspects of care. The third section, Management of Common Serious or Life-Threatening Illnesses, describes pathophysiologies and disease specific management. New in this edition are sections devoted on vulnerable and special populations, and an expanded appendix to include a pharmacological quick reference, a review of oxygen therapy, and other useful references.